weightlossmedication - Naturopathic Weight Loss

September 5, 2024 Naturopathic, GLP-01 Best Weight Loss Drugs, enhancedweightloss, naturopathic supplements, semaglutide, Semaglutide Tirzepatide, weightlossmedication

Can Weight Loss Drugs Really Help with Addiction?

Introduction Who would’ve thought that the same drugs helping people shed pounds might also kick some bad habits out the window? Yep, we’re talking about weight loss meds like Semaglutide and Tirzepatide potentially playing a role in addiction treatment. Sounds wild, right? But there’s some serious science behind this, and researchers are excited about where it might lead. It’s not every day that a medication designed for one thing ends up having the potential to help with something entirely different, but that’s exactly what’s happening here. The Surprising Link Between Weight Loss and Addiction So, what’s the connection? It all starts with a hormone called GLP-1 (glucagon-like peptide-1). Normally, when you eat, your pancreas pumps out GLP-1, which tells your brain, “Hey, you’re full. Put down the spoon!” This signaling is a critical part of keeping our appetite in check. But in people with conditions like obesity or diabetes, this signaling can get a little out of sync, leading to overeating. Your body basically forgets to tell you when you’ve had enough. That’s where weight loss drugs like Semaglutide come in. These drugs mimic GLP-1 to help get those hunger signals back on track. They act like GLP-1’s stunt double, making sure the message gets through loud and clear: Stop eating, you’re good! But here’s where things get interesting—GLP-1 doesn’t just mess with your appetite. It turns out, it also has a hand in how your brain’s reward system works. This is the same system that lights up when you do something that feels good, like eating your favorite food, winning a game, or, unfortunately, using addictive substances like nicotine, alcohol, or drugs. Researchers started to wonder—if GLP-1 can help curb food cravings, could it also help with other cravings? And that’s when things started to get interesting. How Do These Medications Mess with Your Brain? Let’s break it down a bit. The brain’s reward system is all about dopamine, the chemical that makes you feel good. Imagine dopamine as your brain’s way of giving you a high five whenever you do something that’s good for survival, like eating a meal or spending time with loved ones. It’s like a little internal cheerleader, encouraging you to keep doing things that are good for you. Normally, dopamine is great—it makes sure you keep doing things that are important for survival, like eating or socializing. But here’s the catch: addictive substances can hijack this system, making you crave more and more to get that same dopamine hit. It’s like your brain gets stuck in a loop, constantly seeking out the next hit, whether that’s from food, cigarettes, alcohol, or drugs. That’s basically how addiction takes hold. Now, GLP-1 agonists (fancy term for drugs like Semaglutide that mimic GLP-1) might help by reducing how much dopamine your brain pumps out in response to those addictive substances. In simple terms, these drugs could make your brain less excited about nicotine, alcohol, or even opioids, potentially helping to break the cycle of addiction. Imagine if your brain just stopped caring so much about that next cigarette or drink—it could be a game-changer. What’s the Evidence? So, is this all just a theory, or is there some proof? Researchers are on it! In one of the biggest studies so far, scientists tested another GLP-1 drug called exenatide on people with alcohol use disorder. The cool part? When these folks took exenatide, their brains didn’t light up as much when they saw booze, which suggests they weren’t craving it as much. But here’s the twist—this effect was strongest in people who were also dealing with obesity. That’s got researchers scratching their heads. Why would weight influence how well these drugs curb addiction? No one’s totally sure yet, but it could mean that GLP-1 drugs work better for some people than others. Or maybe there’s something special about how obesity and addiction interact. Either way, it’s got scientists eager to dig deeper. And that’s not all—there are studies underway looking at how these drugs might help with other addictions, like smoking and even opioid use. The possibilities are pretty exciting, but there’s still a lot we don’t know. The Safety Question Of course, nothing’s ever that simple, especially when it comes to meds. While GLP-1 drugs are generally safe for people using them to manage weight or diabetes, there are some concerns about using them to treat addiction. For starters, people who are malnourished or have certain health issues might not react well to these drugs. Imagine someone who’s struggling with a drug addiction—they might already be in poor health, and adding a new medication into the mix could have some unexpected effects. Plus, if GLP-1 drugs reduce dopamine too much, there’s a chance they could mess with your mood or motivation. Imagine feeling so “meh” that you lose interest in stuff you used to love—nobody wants that! It’s all about balance, and right now, we don’t know enough about how these drugs might affect people with different health backgrounds or levels of addiction. And let’s not forget about the side effects. Nausea and vomiting are common with these meds, which isn’t exactly fun. If you’re trying to get clean from an addiction, the last thing you need is to feel sick all the time, right? It could be enough to make someone quit the medication altogether, which would be a setback in their recovery journey. A Long Road Ahead So, what’s next? There’s still a lot to figure out. For one, the FDA hasn’t approved GLP-1 drugs for treating addiction yet. And while some researchers are running trials to see how well these drugs work for things like alcohol and opioid addiction, big pharma companies like Novo Nordisk and Eli Lilly are sticking to weight loss and diabetes for now. It’s a bit of a waiting game to see if these drugs really have what it takes to help people struggling with addiction. Even if these drugs do turn out to be a game-changer for addiction,

September 3, 2024 Naturopathic, GLP-01 Best Weight Loss Drugs, enhancedweightloss, naturopathic supplements, semaglutide, Semaglutide Tirzepatide, weightlossmedication

Can’t get insurance to approve weight loss drugs?

If you’ve watched TV or spent any time online lately, you’ve likely seen ads for weight loss drugs. They often highlight the dual benefits of not only shedding pounds but also managing diabetes. The results are undeniable, but there’s one major catch: these drugs come with a steep price tag. And if you’ve tried to get your insurance to cover them, you may have run into some frustrating roadblocks. Up to now, insurers have been reluctant to prescribe them! And in today’s blog, we will discuss the best ways to get your health plan to pay for your prescription and even methods you could use to lower the fees of your medications. Back in the years, weight loss drugs have sometimes been considered a “lifestyle” or “cosmetic” issue. However, the World Health Organization (WHO) recognizes obesity as a chronic disease. This classification highlights that obesity is a long-term, relapsing condition that requires ongoing management, rather than just being a result of lifestyle choices or temporary weight gain. Weight Loss Medication Before we get to the ways to get your health plan to pay for your prescription, we need to understand what weight loss medication we are referring to and who are they geared towards. The category of medication we are talking about are GLP and GLP-1 agonists medication. You may have heard of Semaglutide and Tirzepatide, these are weight loss medications that work by mimicking the effects of a naturally occurring gut hormone. In short, these are FDA-approved medications that contribute to weight loss up to 15 to 20 percent loss of body weight and both Semaglutide and Tirzepatide are both geared toward people with type 2 diabetes. You can find more details about Semaglutide and Tirzepatide if you are interested in our website: https://naturopathicweightloss.com/blog/ What you should know It’s true that many employers and insurance plans don’t cover medications specifically for weight loss. You might wonder, though, if having a prescription from a doctor is enough for an insurer to cover the cost? Well, not necessarily, it is not often the only green light. If your doctor prescribes one of these drugs, there’s usually a process to follow. Often, your doctor will need to get prior authorization from the insurance company to cover the medication. This might involve filling out a form or writing a letter. The insurance plan typically wants to proof that you really need the drug. For example, if you have type 2 diabetes and need GLP-1 medication, you might need to show that you have diabetes and that you’ve tried other diabetes medications without success. They might also check if you meet specific criteria, like having a BMI of 30 or higher, or 27 or higher with a related health condition like high blood pressure. Additionally, they sometimes want to see that you’ve tried other weight loss methods, such as a structured program. Now, if your health plan covers GLP or GLP-1 medication, does that mean you’re off the hook for any out-of-pocket costs? It depends on your health plan. Anyone who has had different health plans knows that out-of-pocket costs can vary widely for the same treatment, depending on your employer or insurance provider. Sometimes, you might just have a flat co-pay like you do for many medications, but since these drugs are expensive, employers are cautious about the costs—both for individual patients and the number of people who might need them. Other options? So, if you’ve found out that your employer and insurance don’t cover your medication, does that mean you’re out of luck and won’t get the treatment you need? Not at all! There are plenty of rebates and discounts offered by manufacturers that can significantly lower the cost of these drugs—sometimes by over 50%. Other alternatives are prescription rate. “If you have diabetes and you can prove it, you can easily register for a prescription rate and receive discounts There are also other methods knowns as co-pay and co-insurance. You may not be aware but your insurance plan might offer different ways to share the cost. Instead of having you pay the full price out-of-pocket, your plan could require a co-pay, which is a fixed amount you pay each time you fill the prescription. For example, you might pay a consistent $20 per refill, regardless of the medication’s actual cost. Alternatively, your plan might involve co-insurance, where you pay a percentage of the medication’s price, such as 20%. This means if semaglutide costs $200, you would pay only $40. It is understandable that all the methods mentioned can become overwhelming as it may involves contacting your insurance, your doctor and filling documents back and forth. There are people who prefer turning to “Buy Now, Pay Later” (BNPL) options to help spread out these costs, making it easier to manage. With BNPL, you can break down the price of your medication into smaller, more affordable payments over time. For example, instead of paying $400 upfront for a month’s supply of semaglutide, you might pay $100 every two weeks for two months. This way, you get the medication you need right away, without straining your budget. Many companies offer these kinds of services, and they often don’t charge interest if you make your payments on time. Conclusion Now the good news: these medications are already approved for treating diabetes and reducing cardiovascular risk, and there are more studies coming out soon that could lead to approvals for other conditions common in people who are obese, like chronic knee pain, osteoarthritis, and sleep apnea. If these new uses get approved, they could end up being covered by insurances. Finger crossed but it seems that over the next few years, we’re likely to see more of these medications being approved and becoming more accessible through healthcare, even if congress doesn’t act right away. So, it’s a good bet that coverage will expand, and more people will be able to access these treatments.

August 22, 2024 Semaglutide, Naturopathic Best Weight Loss Drugs, enhancedweightloss, naturopathic supplements, semaglutide, Semaglutide Tirzepatide, weightlossmedication

How Long Does It Take for Semaglutide to Suppress Appetite?

Table of Contents Table Of Content What is Semaglutide and How Does It Work? How Long Does It Take for Semaglutide to Work? Factors Affecting How Long It Takes Semaglutide to Work What to Expect During the First Few Weeks of Semaglutide Treatment Precautions FAQ You’ve tried diet after diet, workout after workout, but those cravings just won’t quit. Each time you don’t see results, it feels like another letdown, leaving you wondering if anything will really work. Now, semaglutide offers that hope, but the burning question on your mind is, how long does it take for semaglutide to suppress appetite? When you’re fighting those relentless hunger pangs, each day without relief feels unbearable. But you’re not in this alone, and you’re not without help. In this blog post, we will share how long semaglutide takes to work, so you can hold on to that hope just a little longer, knowing that change is on the horizon. What is Semaglutide and How Does It Work? Semaglutide is a medication initially developed to manage type 2 diabetes, but it has also become a powerful tool for weight management. It belongs to a class of drugs called GLP-1 receptor agonists, which mimic the effects of the glucagon-like peptide-1 (GLP-1) hormone naturally produced in your body. This is how it works: 1. Appetite Suppression: Semaglutide works by slowing down digestion and sending signals to your brain that make you feel fuller for longer. This action helps reduce hunger and, consequently, your overall calorie intake. By regulating these hunger signals, semaglutide makes it easier to stick to a healthy eating plan. 2. Blood Sugar Control: Semaglutide also stimulates the pancreas to release more insulin when blood sugar levels are high, helping to lower blood glucose. This dual action is particularly beneficial for individuals with type 2 diabetes, as it not only controls blood sugar but also aids in weight management by reducing appetite. 3. Slows Digestion: Semaglutide ensures that food is released more slowly from the stomach into the intestines by slowing gastric emptying. This slower digestion helps maintain stable blood sugar levels after meals and contributes to a sustained feeling of fullness, making it easier to manage food portions and resist overeating. How Long Does It Take for Semaglutide to Work? How long does semaglutide take to work can vary depending on several factors, but here’s what most people can generally expect: 1. First Few Days to the First Week: Some people notice subtle changes within the first week. You might start to feel a slight reduction in hunger and find it a bit easier to avoid snacking between meals. However, don’t be discouraged if you don’t feel a significant difference right away—this initial period is just the beginning. 2. Weeks 2 to 4: By the second to fourth week, semaglutide typically starts to have a more noticeable effect on your appetite. Many users report feeling fuller after meals and experiencing fewer cravings. This is when you might start to see the real benefits of the medication, making it easier to stick to your dietary goals and reduce your calorie intake. Tip: For even better results, try combining semaglutide with a naturopathic weight loss plan. If you’re curious about how GLP-1 agonists like semaglutide can be part of a broader naturopathic strategy, check out this detailed guide on how GLP-1 agonists support naturopathic weight loss. It’s full of helpful insights. 3. Weeks 5 to 12: As you continue with semaglutide, its appetite-suppressing effects generally become more consistent. Around this time, you might notice a more significant reduction in hunger, leading to steady weight loss. For some, the effects might intensify as the dosage is gradually increased, in line with your healthcare provider’s recommendations. 4. After 12 Weeks: For most users, the long-term benefits of semaglutide begin to solidify after 12 weeks of consistent use. Appetite suppression remains steady, supporting ongoing weight loss and helping to manage food intake more effectively. Research has shown that continuation with semaglutide led to ongoing weight loss over the following 48 weeks, resulting in an average of 17.4% reduction in body weight from baseline. [2] Factors Affecting How Long It Takes Semaglutide to Work The timeline for semaglutide to start working can vary significantly from person to person due to several key factors. 1. Individual Metabolic Rate: Your metabolism plays a crucial role in how quickly you notice the effects of semaglutide. Individuals with a faster metabolic rate may experience the appetite-suppressing effects sooner than those with a slower metabolism. This variability also impacts how fast semaglutide works for different people, as factors like age, genetics, and overall health influence metabolic speed. 2. Lifestyle Choices: Your diet and exercise habits significantly impact how well and how quickly semaglutide works. Combining semaglutide with a balanced diet and regular physical activity can enhance its effectiveness, leading to faster and more pronounced results. Conversely, a sedentary lifestyle or poor dietary choices can delay how fast semaglutide works and make it harder to achieve the desired benefits. 3. Adherence to Prescribed Dosage: The medication typically starts at a lower dose to minimize side effects and is gradually increased. Adults generally begin with 0.25 milligrams (mg) [3] injected under the skin once a week for the first 4 weeks. Your doctor may increase your dose as needed, but the usual maximum dose is 2 mg once a week. Note that missing doses or not following the prescribed schedule can delay the onset of its appetite-suppressing effects. 4. Interaction with Other Medications: If you are taking other medications or have underlying medical conditions, these can interact with semaglutide and affect how quickly it works. Some drugs may slow down the absorption or effectiveness of semaglutide, while others may enhance its effects. 5. Working with a Healthcare Provider: Regular check-ins with your healthcare provider are crucial to monitor your progress and make any necessary adjustments to your treatment. Your provider can help optimize your dosage and address any side effects, ensuring that semaglutide works

August 20, 2024 Naturopathic, Medical enhancedweightloss, naturopathic supplements, Semaglutide Tirzepatide, weightlossmedication

Tirzepatide in treating obstructive sleep apnea and obesity

Table of Contents Table Of Contents What is Sleep Apnea? Sleep Apnea In-depth Sleep Study Methods in the Study The Results Adverse Events Limitations Conclusion This is going to be a different type of blog post. Today we will discuss and summarize a recent paper published on June 21, 2024, in The New England Journal of Medicine exploring Tirzepatide for treating sleep apnea and obesity. Here we go! Approximately 39 million US adults have obstructive sleep apnea, and 936 million adults worldwide are estimated to have mild to severe obstructive sleep apnea. What is sleep apnea? Obstructive sleep apnea is a common condition where the airway gets blocked during sleep, causing breathing to stop and start repeatedly. One of the main risk factors for this condition is obesity. People who are overweight are more likely to have obstructive sleep apnea because the extra weight can put pressure on the airway and make it more likely to collapse during sleep. Hence it was no surprise, that there is a press release about a study that looked at how Tirzepatide affects sleep apnea. Sleep apnea in-depth Before we get to the findings, let’s learn more about sleep apnea. There are two types of sleep apnea. The first type is obstructive sleep apnea, which happens when the upper airway gets blocked during sleep. This blockage interferes with breathing and can cause a person to stop breathing for short periods while asleep. The second type is central sleep apnea. This occurs when the brain doesn’t send the right signals to the muscles that control breathing. As a result, the muscles and nerves aren’t activated enough for breathing, leading to pauses in airflow during sleep. The reason we care about sleep apnea is because, if left untreated, it can lead to many serious health problems. These include insulin resistance, type 2 diabetes, high blood pressure, abnormal cholesterol levels, high blood sugar, stroke, kidney disease, sexual dysfunction, and coronary artery diseases like heart failure. Essentially, untreated sleep apnea can cause a wide range of medical issues. Additionally, several health conditions can increase the risk of developing sleep apnea, such as hypothyroidism, cleft lip or cleft palate, heart disease, kidney disease, large tonsils, obesity or higher body weight, and even menopause. These conditions can either cause sleep apnea or make it worse. Now, how do you know if you have sleep apnea? Some of the most common symptoms include excessive daytime sleepiness, where you go to sleep, wake up, and still feel unrested. You might also experience loud snoring. Another symptom is observed episodes where you stop breathing while sleeping. You might suddenly start breathing again with a gasp, or someone may need to nudge you awake to resume breathing. People with sleep apnea might also wake up gasping or coughing. Additionally, some wake up with a dry mouth or sore throat in the morning. Morning headaches are also a common symptom. Sometimes, difficulty controlling blood pressure can be an indicator of sleep apnea. If you have any of these symptoms, it might be worth consulting a healthcare professional to get evaluated for sleep apnea. Sleep study If you think you might have sleep apnea and want to get diagnosed, the first step is to undergo a sleep study. There are several types of sleep studies available. The most common one is done at a sleep clinic, where you stay overnight. During this study, called polysomnography, they place leads on your head to monitor brain activity, and sensors on your chest to check your heart and breathing. They also measure your oxygen levels while you sleep. Another option is a home sleep test, which you can do in your bed. This test doesn’t use as many sensors. Typically, you’ll wear a device like a watch, have a band around your chest, a sensor in your nose to monitor airflow, and a pulse oximeter on your finger to check oxygen levels. This home test is more convenient and often less expensive than the in-clinic study, depending on your insurance. Both types of tests provide valuable information to help diagnose sleep apnea. As we know, Tirzepatide is a once-weekly GIP and GLP-1 receptor agonist known to lead to a 20% reduction in body weight. If you are familiar with Semaglutide, you can think of Tirzepatide as its younger stronger brother. Methods in the study It is an industry-funded study, it was conducted in two phase 3, double-blind, randomized, controlled trials involving adults with moderate-to-severe obstructive sleep apnea and obesity. The participants were assigned to receive either the maximum tolerated dose of Tirzepatide (10 mg or 15 mg) or a placebo for 52 weeks. In terms of the most salient exclusion criteria, type 1 diabetes, type 2 diabetes, a prior or planned surgery, or if they had a self-reported weight loss of more than 5kg in the past 3 months. The intervention was Tirzepatide, which started at a dose of approximately 2 and a half mg once a week and up to 15 mg once a week and to a comparison of placebo. The outcome was change from the baseline in the Apnea-Hypopnea Index (AHI). In brief, the AHI index is essentially how many times a person stops breathing every hour, it’s assessed with a sleep study. So, all the participants in this study had a sleep study done at the beginning and a follow-up sleep study at the end of the trial. The Results Now, let’s dive into the actual results! They recruited 470 adults, and as noted they were randomized to Tirzepatide or placebo. The average age was 50. 30% were women and 73% were white, the average BMI was 39 and the base AHI index was 50 as a point of reference “AHI above 30 is severe” In other words, this was the real deal in terms of sleep apnea. So, what happened? Well, in the group of Tirzepatide, those patients experienced a 25%-point reduction in their AHI index which is remarkable compared to the placebo

August 15, 2024 Naturopathic glp-1 receptor agonists, naturopathic supplements, semaglutide, Semaglutide Tirzepatide, weightlossmedication

How GLP-1 Agonists Support Naturopathic Weight Loss

Table of Contents Table Of Content What is Naturopathic Weight Loss? What are GLP-1 Agonists? What is the Link Between Naturopathic Weight Loss and GLP-1? Popular GLP-1 Agonists 1. Tirzepatide Diet Plan 2. Semaglutide Diet Plan Could This Be What You’re Missing? In 2021, 38.4 million Americans—11.6% of the population—were living with diabetes. GLP-1 agonists, like Semaglutide and Tirzepatide, were created to help manage this condition. They’re now being used to help with weight loss too. If you’re tired of struggling with diets that don’t work, these medications might be worth a look. In this article, we’ll explore how these medications are incorporated into modern diet plans and what you should know if you’re considering them for your weight loss journey. Read on to see if they could be the solution you need. What is Naturopathic Weight Loss? Naturopathic weight loss is all about using natural ways to help people shed pounds and keep them off. This method combines dietary changes, regular exercise, stress management, and natural supplements. Instead of depending on medications or surgeries, it highlights the importance of consuming whole foods, staying active, and managing stress for sustainable weight loss. A big part of this approach is taking whole grains, fruits, vegetables, nuts, seeds, and legumes, which together support a healthier lifestyle. What are GLP-1 Agonists? GLP-1 agonists are medications that mimic the action of the Glucagon-like Peptide 1 (GLP-1) Hormone in the body. This hormone is produced in the gut and significantly helps manage blood sugar levels and appetite. Here’s how they work: Appetite Control — GLP-1 agonists slow down the emptying of the stomach, which prolongs the feeling of fullness after meals. This reduced hunger leads to lower calorie intake, which is essential for weight loss. Blood Sugar Regulation — These medications increase the release of insulin in response to food, helping to manage blood sugar levels more effectively. Stable blood sugar levels are crucial for preventing excessive hunger and energy crashes, which can lead to overeating. Reduced Glucagon Secretion — GLP-1 agonists reduce the secretion of glucagon, a hormone that prevents the liver from releasing too much glucose into the blood. This helps maintain lower blood sugar levels, further aiding in weight control. Dosage info — These medications are typically administered as injections (weekly or daily), though some are available as daily pills. While they are generally effective, side effects like nausea and digestive discomfort may occur but often improve over time. What is the Link Between Naturopathic Weight Loss and GLP-1? The connection between naturopathic weight loss and GLP-1 agonists lies in their complementary approach to managing weight. When GLP-1 agonists are integrated into a naturopathic weight loss plan, they can support the body’s natural processes by helping to control hunger and improve insulin sensitivity. This combination of natural methods and medication can offer a more balanced and effective approach to weight loss, especially for those who struggle with obesity or have related health issues. Popular GLP-1 Agonists Tirzepatide and Semaglutide are two of the most widely used GLP-1 agonists in weight loss and diabetes management. Tirzepatide is unique because it is a dual agonist and targets both GLP-1 and GIP (glucose-dependent insulinotropic polypeptide) receptors. This dual action leads to more significant weight loss compared to Semaglutide. Tirzepatide is also under consideration for FDA approval specifically for weight loss which adds to its growing reputation as a powerful option for obesity management. Semaglutide, on the other hand, solely targets the GLP-1 receptor. It has been extensively studied and is currently approved for both type 2 diabetes and obesity management. Its long track record provides a solid understanding of its efficacy and makes it a reliable choice for many patients. Note: Both medications are effective, but Tirzepatide generally offers greater weight loss, though it may also have a higher risk of gastrointestinal side effects like nausea and vomiting. The choice between these medications should be based on individual health needs, potential side effects, and consultation with a healthcare provider. 1. Tirzepatide Diet Plan Tirzepatide helps reduce body weight by making you feel fuller for longer and curbing your appetite. This reduces the overall calorie intake, making it easier to stick to a diet and achieve sustainable weight loss. Studies have shown that Tirzepatide can lead to a 20% reduction in body weight in patients, which is higher than what’s typically seen with other weight loss medications like Semaglutide. If Tirzepatide feels right for you, check it out here. You can follow these dietary guidelines to get the most out of Tirzepatide: Focus on vegetables, fruits, lean proteins, and whole grains. These foods help stabilize blood sugar levels and complement Tirzepatide’s appetite-suppressing effects. Include sources like avocados, nuts, and olive oil. These fats contribute to satiety and do not cause significant blood sugar spikes, supporting Tirzepatide’s benefits. Go for complex carbohydrates like brown rice, quinoa, and sweet potatoes. These carbs release sugar slowly and can help prevent blood sugar spikes that can undermine the effects of Tirzepatide. Drink plenty of water to aid digestion and support Tirzepatide’s effectiveness. Proper hydration also helps manage any gastrointestinal side effects. These foods can lead to digestive issues, particularly when combined with Tirzepatide. So, it will be wiser to stick to lighter and less processed options. 2. Semaglutide Diet Plan Semaglutide is a GLP-1 agonist that supports weight loss by reducing appetite, slowing stomach emptying, and helping regulate blood sugar levels. However, It’s essential to pair it with an appropriate diet plan that complements these effects to get the best results from Semaglutide. Semaglutide helps reduce body weight by about 12-13% on average at the highest doses. You can follow these dietary guidelines to get the most out of Semaglutide: Prioritize a diet rich in vegetables, fruits, lean proteins, and whole grains. These foods help stabilize blood sugar levels and enhance the appetite-suppressing effects of Semaglutide. Add lean meats like chicken, turkey, and fish, as well as plant-based proteins like beans and lentils. Protein helps maintain muscle mass during

August 13, 2024 Sleep naturopathic supplements, weightlossmedication

Tirzepatide in treating obstructive sleep apnea and obesity

Table of Contents Table Of Content Sleep apnea in-depth Sleep study Methods in the study The Results Adverse events Limitation Conclusion This is going to be a different type of blog post. Today we will discuss and summarize a recent paper published on June 21, 2024, in The New England Journal of Medicine exploring Tirzepatide for treating sleep apnea and obesity. Here we go! Approximately 39 million US adults have obstructive sleep apnea, and 936 million adults worldwide are estimated to have mild to severe obstructive sleep apnea. What is sleep apnea? Obstructive sleep apnea is a common condition where the airway gets blocked during sleep, causing breathing to stop and start repeatedly. One of the main risk factors for this condition is obesity. People who are overweight are more likely to have obstructive sleep apnea because the extra weight can put pressure on the airway and make it more likely to collapse during sleep. Hence it was no surprise, that there is a press release about a study that looked at how Tirzepatide affects sleep apnea. Sleep apnea in-depth Before we get to the findings, let’s learn more about sleep apnea. There are two types of sleep apnea. The first type is obstructive sleep apnea, which happens when the upper airway gets blocked during sleep. This blockage interferes with breathing and can cause a person to stop breathing for short periods while asleep. The second type is central sleep apnea. This occurs when the brain doesn’t send the right signals to the muscles that control breathing. As a result, the muscles and nerves aren’t activated enough for breathing, leading to pauses in airflow during sleep. The reason we care about sleep apnea is because, if left untreated, it can lead to many serious health problems. These include insulin resistance, type 2 diabetes, high blood pressure, abnormal cholesterol levels, high blood sugar, stroke, kidney disease, sexual dysfunction, and coronary artery diseases like heart failure. Essentially, untreated sleep apnea can cause a wide range of medical issues. Additionally, several health conditions can increase the risk of developing sleep apnea, such as hypothyroidism, cleft lip or cleft palate, heart disease, kidney disease, large tonsils, obesity or higher body weight, and even menopause. These conditions can either cause sleep apnea or make it worse. Now, how do you know if you have sleep apnea? Some of the most common symptoms include excessive daytime sleepiness, where you go to sleep, wake up, and still feel unrested. You might also experience loud snoring. Another symptom is observed episodes where you stop breathing while sleeping. You might suddenly start breathing again with a gasp, or someone may need to nudge you awake to resume breathing. People with sleep apnea might also wake up gasping or coughing. Additionally, some wake up with a dry mouth or sore throat in the morning. Morning headaches are also a common symptom. Sometimes, difficulty controlling blood pressure can be an indicator of sleep apnea. If you have any of these symptoms, it might be worth consulting a healthcare professional to get evaluated for sleep apnea. Sleep study If you think you might have sleep apnea and want to get diagnosed, the first step is to undergo a sleep study. There are several types of sleep studies available. The most common one is done at a sleep clinic, where you stay overnight. During this study, called polysomnography, they place leads on your head to monitor brain activity, and sensors on your chest to check your heart and breathing. They also measure your oxygen levels while you sleep. Another option is a home sleep test, which you can do in your bed. This test doesn’t use as many sensors. Typically, you’ll wear a device like a watch, have a band around your chest, a sensor in your nose to monitor airflow, and a pulse oximeter on your finger to check oxygen levels. This home test is more convenient and often less expensive than the in-clinic study, depending on your insurance. Both types of tests provide valuable information to help diagnose sleep apnea. As we know, Tirzepatide is a once-weekly GIP and GLP-1 receptor agonist known to lead to a 20% reduction in body weight. If you are familiar with Semaglutide, you can think of Tirzepatide as its younger stronger brother. Methods in the study It is an industry-funded study, it was conducted in two phase 3, double-blind, randomized, controlled trials involving adults with moderate-to-severe obstructive sleep apnea and obesity. The participants were assigned to receive either the maximum tolerated dose of Tirzepatide (10 mg or 15 mg) or a placebo for 52 weeks. In terms of the most salient exclusion criteria, type 1 diabetes, type 2 diabetes, a prior or planned surgery, or if they had a self-reported weight loss of more than 5kg in the past 3 months. The intervention was Tirzepatide, which started at a dose of approximately 2 and a half mg once a week and up to 15 mg once a week and to a comparison of placebo. The outcome was change from the baseline in the Apnea-Hypopnea Index (AHI). In brief, the AHI index is essentially how many times a person stops breathing every hour, it’s assessed with a sleep study. So, all the participants in this study had a sleep study done at the beginning and a follow-up sleep study at the end of the trial. The Results Now, let’s dive into the actual results! They recruited 470 adults, and as noted they were randomized to Tirzepatide or placebo. The average age was 50. 30% were women and 73% were white, the average BMI was 39 and the base AHI index was 50 as a point of reference “AHI above 30 is severe” In other words, this was the real deal in terms of sleep apnea. So, what happened? Well, in the group of Tirzepatide, those patients experienced a 25%-point reduction in their AHI index which is remarkable compared to the placebo which was only a

May 30, 2024 Naturopathic Best Weight Loss Drugs, enhancedweightloss, semaglutide, Semaglutide Tirzepatide, weightlossmedication

How Long Does a Vial of Semaglutide Last – Understanding the Shelf Life of Semaglutide!

Table of Contents Table Of Content Factors Affecting Semaglutide Vial Longevity Expiration Date and Manufacturer Guidelines Storage Conditions Handling Practices Dosage Regimen Vial Concentration and Size Take Away Frequently Asked Questions Semaglutide has revolutionized the management of type 2 diabetes and obesity, offering significant benefits with regular use. Knowing the duration each vial lasts can help you maintain a seamless treatment schedule and maximize the medication’s effectiveness. Wondering how long does a vial of Semaglutide last? A vial of Semaglutide lasts for up to 56 days after opening, provided it is stored at room temperature (up to 86°F or 30°C) or refrigerated between 36°F to 46°F (2°C to 8°C). Unopened vials should be refrigerated only and can be kept until their expiration date. If necessary, Wegovy can last 28 days if kept at room temperature. Dive into this comprehensive guide to learn how dosage, frequency, and proper storage determine how long a vial of Semaglutide will last. Get empowered with the knowledge to manage your treatment more effectively and maintain optimal health. Factors Affecting Semaglutide Vial Longevity 1. Expiration Date and Manufacturer Guidelines Semaglutide vials are labeled with an expiration date, which should be the first indicator of its shelf life. Unopened Semaglutide vials should not be used past this date. The manufacturers rigorously test the stability of the medication under various conditions to determine this date, ensuring the safety and effectiveness of the medication up to this point. 2. Storage Conditions Improperly stored Semaglutide vials should be disposed of immediately. However, mind that Semaglutide injections can remain effective even if exposed to temperatures as high as 104°F (40°C) for up to three days. If your vials arrive warm, they are still safe to use, provided you transfer them to refrigerated conditions of 36-46°F (2-8°C) immediately upon receiving. Opened Semaglutide vials last for up to 56 days if stored in the refrigerator between 2°C to 8°C or at room temperature below 30°C. Unopened vials should be refrigerated only and last till its expiry, except Wegovy which can be kept at room temperature if necessary and can last up to 28 days. It’s critical to keep the vial away from light and to avoid freezing it, as this can degrade its effectiveness. 3. Handling Practices Proper handling of Semaglutide is crucial. Avoid shaking the vial vigorously as this can affect the medication’s integrity. Always use sterile needles and practice good hygiene when administering injections to prevent contamination. Improperly handled vials won’t last long. 4. Dosage Regimen The primary determinant of how long a vial of Semaglutide lasts is the prescribed dosage. Semaglutide is typically administered once a week, and the dosage can vary based on the specific needs of the patient. Common starting doses for Semaglutide, for instance, are 0.25 mg per week for the first four weeks, followed by an increase to 0.5 mg. Depending on the therapeutic goals, the dose can be further increased to 1 mg (higher maintenance dose) or 2.4 mg per week (primarily for weight management under the brand name Wegovy) Brand and Concentration Dose How long will one vial last? Ozempic:1.5 mL vial contains 2 mg of Semaglutide 0.25 mg/ weekly 8 weeks 0.5 mg/ weekly 4 weeks Wegovy:4 mL vial contains 10 mg of Semaglutide 2.4 mg /weekly 4 weeks 5. Vial Concentration and Size The concentration of Semaglutide in a vial also plays a critical role. For example, Ozempic is available in different strengths, such as 1.5 mg/1.5 mL (1 mg/mL) and 4 mg/3 mL (1.34 mg/mL). The size of the vial dictates how many doses can be extracted. Typically, a single vial of Ozempic contains multiple doses. Take Away For Semaglutide users, understanding the storage, handling, and expiration of the medication is key to ensuring its efficacy and safety. Always adhere to the storage instructions and use the medication within the recommended period after opening. If in doubt, consult your healthcare provider for guidance on how to manage your Semaglutide treatment effectively. Frequently Asked Questions How to properly store Semaglutide vial? To properly store unopened Semaglutide vial, keep it in the refrigerator between 2°C to 8°C (36°F to 46°F). However, Wegovy can be stored outside at room temperature too, if necessary, for 28 days. Opened Semaglutide vials can be either kept at room temperature (below 30°C/86°F) or in the refrigerator lasting for 56 days after it is first used Why is my Semiglutide vial solution discolored or cloudy? A discolored or cloudy Semaglutide vial solution indicates potential degradation or contamination, which can occur due to improper storage, exposure to extreme temperatures, or the vial being past its expiration date. Do not use the solution and contact your healthcare provider or pharmacist for guidance and a replacement Can I use Semaglutide after it has expired? No, it is not recommended to use Semaglutide after it has expired. Expired medications may lose potency, reducing their effectiveness, and could potentially cause adverse effects. Always check expiration dates and consult with a healthcare provider for safe and effective treatment options. What to do if my Semaglutide is expired? If your Semaglutide has expired, do not use it. Dispose of it according to local guidelines or return it to a pharmacy for safe disposal. Contact your healthcare provider to obtain a new prescription to ensure safe and effective treatment. How to dispose of expired or improperly stored Semaglutide? To dispose of expired or improperly stored Semaglutide, do not flush it down the toilet. Use local medication take-back programs or DEA-authorized collection sites if available. If these options are not accessible, mix the medication with an unappealing substance like coffee grounds or cat litter, seal it in a plastic bag, and dispose of it in your household trash.

May 30, 2024 Naturopathic Best Weight Loss Drugs, enhancedweightloss, semaglutide, Semaglutide Tirzepatide, weightlossmedication

Step-By-Step Guide On How to Properly Mix 5mg of Semaglutide with Bacteriostatic Water?

Table of Contents Table Of Content Understanding Semaglutide Why Bacteriostatic Water? How Much Bacteriostatic Water to Mix With 5mg of Semaglutide? Mixing Semaglutide with Bacteriostatic Water Semaglutide Syringe Units Where Can I Buy Semaglutide Online? Conclusion Frequently Asked Questions Are you sure you are mixing enough bacteriostatic water with semaglutide to reap its benefits for weight loss and type 2 diabetes? Mixing the correct amount of bacteriostatic water with your 5mg vial of Semaglutide is crucial for ensuring the medication’s effectiveness and safety. Wondering what exactly is the right ratio and how much bacteriostatic water to mix with 5mg of semaglutide? To mix 5mg of Semaglutide with bacteriostatic water, take a ratio of 1:1. Draw 5mL of bacteriostatic water using a sterile syringe and inject it into the 5mg Semaglutide vial. Aim the water against the vial wall to minimize foaming and gently swirl until fully dissolved. This will create a solution with a 1mg/mL concentration. In this guide, we’ll walk you through the precise method for mixing bacteriostatic water with a 5mg vial of Semaglutide. By following these simple steps, you’ll be able to prepare your medication with ease and assurance. Let’s get started on this straightforward yet essential process for your health journey. Understanding Semaglutide Semaglutide belongs to a class of medications known as GLP-1 receptor agonists. It works by mimicking the action of the glucagon-like peptide-1 (GLP-1), which helps to regulate blood sugar levels. When prepared for injection, Semaglutide typically comes in a powdered form that requires reconstitution with a suitable liquid. Why Bacteriostatic Water? Bacteriostatic water is a sterile water solution that contains 0.9% benzyl alcohol, which inhibits the growth of bacteria. This makes it a suitable and safe option for mixing with medications that are intended for injection, especially those that will be stored for multiple uses over several days or weeks. How Much Bacteriostatic Water to Mix With 5mg of Semaglutide? To mix 5mg of Semaglutide with bacteriostatic water, follow these steps: Mixing Semaglutide with Bacteriostatic Water If you have a 5mg vial of Semaglutide and wish to prepare a 1mg/mL solution: You now have a solution where 1mL contains 1mg of Semaglutide. For dosing, you would draw up the required volume based on your prescribed dosage. For instance, if your prescribed dose is 0.25mg, you would draw 0.25mL of the prepared solution. Semaglutide Syringe Units The starting dose for both type 2 diabetes and weight management is 0.25 mg once weekly for 4 weeks. The dose is then increased every 4 weeks (0.5 mg, 1.0 mg, 1.7 mg, and finally 2.4 mg) until the maintenance dose of 2.4 mg once weekly is reached. Where Can I Buy Semaglutide Online? You can buy the cheapest semaglutide online from Naturopathic Weight Loss. We are a reputable online pharmacy that offers top-quality supplements at competitive prices. Enjoy quick delivery and discreet packaging to maintain your privacy. Just visit our website, add your items to the cart, and complete your purchase. Your order will be promptly shipped right to your doorstep. Conclusion Mixing Semaglutide with bacteriostatic water is a straightforward process that requires careful measurement and aseptic techniques. By ensuring the correct concentration and proper handling, you can safely prepare and administer your medication. Always follow your healthcare provider’s instructions and consult them if you have any uncertainties about the process. Frequently Asked Questions Can I use sterile water instead of bacteriostatic water for mixing with Semaglutide? No, it is not recommended to use sterile water instead of bacteriostatic water for mixing with Semaglutide. Bacteriostatic water contains a preservative that prevents bacterial growth, making it safer for use in medications that might be stored and used over a period of time. Sterile water, while free of bacteria, does not contain these preservatives. How should I store the Semaglutide solution after mixing it with bacteriostatic water? Once mixed, the Semaglutide solution should be used within a specified time frame and stored according to the manufacturer’s instructions, typically in a refrigerator. Can bacteriostatic water be used multiple times for different medication vials? Yes, bacteriostatic water can be used multiple times for different medication vials due to its preservative that inhibits bacterial growth. Ensure proper aseptic technique by using a new, sterile needle for each use and disinfecting the vial’s stopper with alcohol before piercing. How should bacteriostatic water be stored after opening? After opening, bacteriostatic water should be stored in a cool, dark place, either at room temperature or in the refrigerator, and it should be used or discarded within 28 days to ensure safety. Make sure the cap is securely tightened to avoid contamination.

May 21, 2024 Naturopathic Best Weight Loss Drugs, Choosing the Best Weight Loss Drug: Semaglutide Or Tirzepatide, enhancedweightloss, Semaglutide Tirzepatide, tirzepatide, weightlossmedication

Choosing the Best Weight Loss Drug: Semaglutide Or Tirzepatide

Semaglutide or Tirzepatide, Find out which works better for weight loss. Study facts, effectiveness, and long-term impacts before making any decision. Introduction An appropriate agent is crucial for optimal weight reduction. Interventions that significantly and sustainably reduce weight are needed to combat obesity and its comorbidities. Choosing the right weight loss agent helps to achieve goals and improve health. This choice must include effectiveness, safety, tolerability, and patient preferences. Weight control drugs Semaglutide and Tirzepatide are promising. Both are GLP-1 receptor agonists that improve weight reduction. Weight management decisions need knowledge of their methods of action, clinical characteristics, and comparative efficacy. Knowing Semaglutide for Weight Loss Action Mechanism: Semaglutide as a GLP-1 receptor agonist works by letting the central nervous system stimulate insulin production, suppress glucagon release, and reduce hunger. Weight Loss Trial Clinical Efficacy: Semaglutide outperforms placebo in clinical studies, including the STEP program, in weight reduction. Concerns about safety Nausea, vomiting, and diarrhea usually subside. Pancreatitis and thyroid cancers are infrequent but dangerous adverse effects that must be monitored. Weight Management Dosing and Administration: Each week, semaglutide is subcutaneously injected and progressively titrated to reduce gastrointestinal adverse effects and maximize weight reduction. Knowing Tirzepatide for Weight Loss Action Mechanism: Tirzepatide is a dual glucose-dependent insulinotropic polypeptide (GIP) and GLP-1 receptor agonist that regulates appetite, glucose metabolism, and energy balance. Weight Loss Trial Clinical Efficacy: SURPASS and SURMOUNT showed that Tirzepatide outperformed placebo and comparative medicines in weight reduction. Concerns about safety Nausea, vomiting, and increased heart rate are common side effects. Hypoglycemia and metabolic consequences must be monitored. Weight Management Dosing and Administration: Initial titration of tripeptide subcutaneously once weekly reduces gastrointestinal adverse effects and optimizes weight reduction. Does Either Drug Have Side Effects? Semaglutide and Tirzepatide have adverse effects. Check the side effects. Tirzepatide Semaglutide Comparison of Weight Loss One-on-one weight loss efficacy comparison: In direct comparative studies, both semaglutide and Tirzepatide promote weight reduction. However, the degree and rate of weight loss may vary. Comparing Safety Profiles: Both Semaglutide and Tirzepatide have similar safety profiles, including nausea and vomiting. These side effects and other safety concerns, including cardiovascular consequences, may vary in prevalence and severity. Dosing schemes: Considerations for Weight Control: Semaglutide or Tirzepatide have identical once-weekly subcutaneous doses for weight control. Titration tactics to reduce gastrointestinal side effects and optimize weight reduction and patient adherence are practical issues. Considerations for Patients Factors Influencing the Choice Between Semaglutide Or Tirzepatide for Weight Loss: Considering patient preferences and lifestyle: When deciding between Semaglutide and Tirzepatide, patient preferences for dose frequency, method of administration, and lifestyle variables, including food and exercise, should be considered. Special Populations and Weight Management Comorbidities: Semaglutide and Tirzepatide weight control for patients with diabetes, cardiovascular disease, or renal impairment may need individualized methods due to possible interactions and safety profiles. Weight Loss Costs and Access Compare Weight Loss Cost-Effectiveness: The cost-effectiveness of Semaglutide and Tirzepatide depends on medication procurement costs, weight reduction-related health savings, and therapy success. Weight Loss Insurance Considerations: Patient access to Semaglutide and Tirzepatide depends on insurance coverage. Indication approvals, formulary inclusion, prior authorization, and patient eligibility affect coverage. Weight Management Program and Clinical Practice Accessibility: Semaglutide and Tirzepatide are available in weight management programs and clinical practices depending on medication availability, healthcare professional training, patient education, and reimbursement support. Semaglutide vs. Tirzepatide: SURPASS-2 study The SURPASS-2 research compares the effectiveness and safety of GLP-1 receptor agonists Semaglutide and Tirzepatide for type 2 diabetes. It measures diabetes participants’ glucose control, weight reduction, and adverse events. The research compares Semaglutide with Tirzepatide for diabetes and comorbidities. Future Weight Loss Prospects In weight control, Semaglutide is being studied for optimal dose, combination therapy, and long-term safety and effectiveness. Research on Tirzepatide continues to improve dose, discover new indications, and explain its weight loss process. Personalized weight reduction treatments using genetic and metabolic profiling are expected. Digital health technology and behavioral therapies may improve obesity treatment adherence and long-term results. Which Drug is More Effective? Numerous studies show that Tirzepatide is more effective than Semaglutide for weight loss. Semaglutide has been available for a longer time; therefore, its long-term effects are well understood. Tirzepatide may show encouraging short-term benefits, but its long-term safety and effectiveness are currently being explored. Thus, while treating weight loss patients, doctors must measure Tirzepatide’s immediate advantages against Semaglutide’s proven efficacy. Research at the Mayo Foundation for Medical Education and Research (MFMER) (https://www.mayoclinic.org/drugs-supplements/teriparatide-subcutaneous-route/proper-use/drg-20066280) shows that tripeptide reduces weight, while semaglutide reduces body weight better than other drugs. Conclusion Semaglutide and Tirzepatide are effective for weight reduction; however, their mechanisms of action, dosage regimens, and safety profiles vary. Healthcare professionals should choose a weight loss agent based on patient response, tolerability, cost, and insurance coverage. Thorough evaluations of these criteria and shared decision-making with patients may enhance treatment results, patient satisfaction, and adherence.

May 16, 2024 GLP-01 weightlossmedication

The Powerful Science Behind Weight Loss Medication

Fighting against obesity is a challenging issue. This blog post aims to help you obtain a better understanding of the effects of weight loss medication on obesity and overweight Discover your hormonesGlucagon-like peptide-1 (GLP-1) and gastric inhibitory polypeptide (GIP) are two of the main incretin peptide hormones that are responsible for glucose homeostasis and enhance glucose-stimulated insulin secretion after nutrient ingest. It is the successful application of incretin peptide hormones that have the potential to reduce weight and is considered an obesity treatment. GLP-1GLP-1 hormone is secreted predominantly in response to food intake to stimulate multiple glucose-lowering actions. Such as the secretion of glucose-insulin, delay in gastric emptying, and inhibition of glucagon secretion GIPOn the other hand, GIP is a peptide that is secreted in response to nutrient ingestion. GIP stimulates insulin secretion but does not change glucagon release during hyperglycemia (high levels of glucose in the blood), whereas it increases glucagon release without affecting insulin secretion during hypoglycemia (low levels of glucose in the blood). Peptide hormones using medicationNow, that you know which hormones are responsible for weight loss, the science behind weight loss medication becomes clearer. Recent evidence has shown that the combination of both GIP and GLP-1 through multiple metabolic mechanisms synergistically affect each other. In other words, they have a greater impact on the effectiveness of weight loss and glycemia. Additionally, the infusion of GLP-1 and GIP results in reduced food intake and appetite, thus lowering weight loss. The only FDA-approved medicine as a dual agonist of GIP and GLP-1, used for weight loss and T2D is known as Tirzepatide. Tirzepatide a promising anti-obesity therapeutic drug Analyses revealed that weight loss is particularly impacted by the dosage and duration of the Tirzepatide drug. Are you curious about what happens to your energy intake during treatment? Mechanistic studies have shown that tirzepatide 15 mg once a week reduces energy intake (–348.4 kcal) at full lunch in people with type 2 diabetes through reduction of the overall appetite, which explains the weight reduction. Semaglutide vs. Tirzepatide: Discover the Scientific DifferencesBoth semaglutide and tirzepatide have a strong effect on reducing glucose and body weight. Clinical studies have difficulties comparing both medications as more studies to confirm the findings are required. Nevertheless, here’s what the analysis revealed. In summary, understanding the role of GLP-1 and GIP in weight management opens new avenues for effective obesity treatment. Medications like Tirzepatide represent a significant advancement in obesity therapeutics, providing a scientifically-backed solution for those struggling with weight loss and associated metabolic conditions. As research continues, these medications offer a beacon of hope for improved health outcomes and better quality of life. Interested in learning more about the which medication might help you lose weight?Send us a message right away to get a free consultation from a weight loss expert or if you’re ready to start you journey check out our plans.

Tag: weightlossmedication