Injectable anti-diabetic medications known as glucagon-like peptide-1 (GLP-1) receptor agonists help patients with type 2 diabetes (T2D) achieve better glycemic control and many other atherosclerosis-related metrics. Nonetheless, there might be potential negative consequences from using this relatively new class of medications. Since GLP-1 receptor agonists have been linked to pancreatitis, pancreatic cancer, and thyroid cancer in animal studies and drug database analysis, concerns have been raised about these medications’ impact on pancreatic and thyroid tissue. Nevertheless, a number of meta-analyses were unable to establish a causal relationship between GLP-1 receptor agonists and the emergence of these negative effects.

Side Effects and Supplements:

During GLP-1 receptor agonist clinical trials , the most commonly reported side effects were digestive issues. Probiotic pills with beneficial bacteria may help decrease symptoms of gastrointestinal side effects including nausea and diarrhea by restoring the balance of gut flora.

A. Nausea:

1. Ginger is a well-known remedy for nausea and has additional health benefits. It can be purchased in a tincture, tea, or pill form.
   (Dosage: 250–500 mg of powdered ginger extract or rhizomes up to four times per day.)
   
2. Peppermint: Taking peppermint tea or supplements might help soothe upset stomachs and perhaps reduce nausea.
   (Dosage: Take enteric-coated peppermint oil capsules (0.2-4 mL) twice or three times a day, or use peppermint tea as needed to treat dyspepsia.)
   
3. Vitamin B6: Some people take it to treat nausea, while others use it to treat stomach-related issues including nausea brought on by pregnancy.
   (Dosage: 25–50 mg of this medication may be used orally up to three times a day.)

B. Diarrhea:

It’s also important to know that probiotics can improve digestion and have a favorable effect on the balance of good bacteria in the stomach.

i. Multiple Strains of Probiotics:

Follow are the instructions on the packaging.

1. Psyllium Husk: This type of dietary fiber can assist avoid diarrhea and give stool bulk for hard stools.
   (Dosage: One tablespoon of psyllium husk powder in a glass of water in the morning or evening; one tablespoon of powdered flaxseed with water, ideally in the morning and evening.)
   
2. Chamomile: It could help reduce inflammation and balance digestion since this tea contains different types of acids.
   (Dosage: Take chamomile tea twice a day, one in the morning before breakfast and second in the night before going to sleep.)

ii. Pain in the Abdomen:

1. Peppermint Oil: Peppermint oil capsules coated with enteric cover for gastrointestinal tract spasms are among the treatments for gastroenterological conditions and eradicate discomfort.
   
2. Fennel: Fennel tea or seeds can rectify any kind of bloating or abdominal pain that should not be ignored.
   
3. Aloe Vera: Some benefits of Aloe Vera however include the fact that it has been found to have properties that may help to control inflammation of the gastrointestinal tract.

iii. Overall Assistance with Digestion:

1. Digestive Enzymes: Thus, digestion enzymes help in digestion and therefore reduce any side effects that may be occasioned by taking the supplements with foods.
   
2. DGL (Deglycyrrhizinated Licorice): This can be beneficial in the management of a variety of conditions que es indigestion affecting the gastrointestinal tract and may even have a sedating effect on the digestive organs.

Conclusion:

Therefore, like it is often recommended with any new supplement, it is always wise to consult a doctor, especially if the patient is diabetic or has other chronic diseases that require they take other medications. It will be possible for them to ensure you that no harm comes with the vitamins or any other medication that you are currently taking.