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Category: GLP-01

How to Address Common Side Effects of Glp-01s with Naturopathic Supplements?
June 13, 2024 GLP-01 , , Featured

How to Address Common Side Effects of Glp-01s with Naturopathic Supplements?

Table of Contents Table Of Content Side Effects and Supplements Nausea Diarrhea Multiple Strains of Probiotics Pain in the Abdomen Overall Assistance with Digestion Conclusion Injectable anti-diabetic medications known as glucagon-like peptide-1 (GLP-1) receptor agonists help patients with type 2 diabetes (T2D) achieve better glycemic control and many other atherosclerosis-related metrics. Nonetheless, there might be potential negative consequences from using this relatively new class of medications. Since GLP-1 receptor agonists have been linked to pancreatitis, pancreatic cancer, and thyroid cancer in animal studies and drug database analysis, concerns have been raised about these medications’ impact on pancreatic and thyroid tissue. Nevertheless, a number of meta-analyses were unable to establish a causal relationship between GLP-1 receptor agonists and the emergence of these negative effects. Side Effects and Supplements: During GLP-1 receptor agonist clinical trials , the most commonly reported side effects were digestive issues. Probiotic pills with beneficial bacteria may help decrease symptoms of gastrointestinal side effects including nausea and diarrhea by restoring the balance of gut flora. A. Nausea: B. Diarrhea: It’s also important to know that probiotics can improve digestion and have a favorable effect on the balance of good bacteria in the stomach. i. Multiple Strains of Probiotics: Follow are the instructions on the packaging. ii. Pain in the Abdomen: iii. Overall Assistance with Digestion: Conclusion: Therefore, like it is often recommended with any new supplement, it is always wise to consult a doctor, especially if the patient is diabetic or has other chronic diseases that require they take other medications. It will be possible for them to ensure you that no harm comes with the vitamins or any other medication that you are currently taking.

The Powerful Science Behind Weight Loss Medication
May 16, 2024 GLP-01

The Powerful Science Behind Weight Loss Medication

Fighting against obesity is a challenging issue. This blog post aims to help you obtain a better understanding of the effects of weight loss medication on obesity and overweight Discover your hormonesGlucagon-like peptide-1 (GLP-1) and gastric inhibitory polypeptide (GIP) are two of the main incretin peptide hormones that are responsible for glucose homeostasis and enhance glucose-stimulated insulin secretion after nutrient ingest.  It is the successful application of incretin peptide hormones that have the potential to reduce weight and is considered an obesity treatment. GLP-1GLP-1 hormone is secreted predominantly in response to food intake to stimulate multiple glucose-lowering actions. Such as the secretion of glucose-insulin, delay in gastric emptying, and inhibition of glucagon secretion GIPOn the other hand, GIP is a peptide that is secreted in response to nutrient ingestion. GIP stimulates insulin secretion but does not change glucagon release during hyperglycemia (high levels of glucose in the blood), whereas it increases glucagon release without affecting insulin secretion during hypoglycemia (low levels of glucose in the blood). Peptide hormones using medicationNow, that you know which hormones are responsible for weight loss, the science behind weight loss medication becomes clearer. Recent evidence has shown that the combination of both GIP and GLP-1 through multiple metabolic mechanisms synergistically affect each other. In other words, they have a greater impact on the effectiveness of weight loss and glycemia. Additionally, the infusion of GLP-1 and GIP results in reduced food intake and appetite, thus lowering weight loss. The only FDA-approved medicine as a dual agonist of GIP and GLP-1, used for weight loss and T2D is known as Tirzepatide. Tirzepatide a promising anti-obesity therapeutic drug Analyses revealed that weight loss is particularly impacted by the dosage and duration of the Tirzepatide drug. Are you curious about what happens to your energy intake during treatment? Mechanistic studies have shown that tirzepatide 15 mg once a week reduces energy intake (–348.4 kcal) at full lunch in people with type 2 diabetes through reduction of the overall appetite, which explains the weight reduction. Semaglutide vs. Tirzepatide: Discover the Scientific DifferencesBoth semaglutide and tirzepatide have a strong effect on reducing glucose and body weight. Clinical studies have difficulties comparing both medications as more studies to confirm the findings are required. Nevertheless, here’s what the analysis revealed. In summary, understanding the role of GLP-1 and GIP in weight management opens new avenues for effective obesity treatment. Medications like Tirzepatide represent a significant advancement in obesity therapeutics, providing a scientifically-backed solution for those struggling with weight loss and associated metabolic conditions. As research continues, these medications offer a beacon of hope for improved health outcomes and better quality of life. Interested in learning more about the which medication might help you lose weight?Send us a message right away to get a free consultation from a weight loss expert or if you’re ready to start you journey check out our plans.

Semaglutide or Tirzepatide? Is Weight Loss Medication Right for You?
May 6, 2024 Naturopathic, GLP-01 , ,

Semaglutide or Tirzepatide? Is Weight Loss Medication Right for You?

In a world where obesity is increasingly impairing health and many daily activities, a lot of people are turning to medical diagnoses seeking solutions to halt overweight consequences. The introduction of clinical weight loss drugs has seen new indications and concerns. In 2021, (FDA) Food & Drug Administration approved the very first under-the-skin injection, Wegovy (semaglutide), for chronic weight management in patients with a BMI of 27 kg/m2 or greater and to those linked to at least one “weight-related” health condition like high blood pressure diabetes or cholesterol while in 2022,  Zepbound (tirzepatide) injection was also approved by the FDA for the same conditions. Understanding weight loss medication  John Sharretts, M.D., deputy director of the Division of Diabetes, Lipid Disorders, and Obesity in the FDA’s Center for Drug Evaluation and Research says the approvals of the drug offer adults with obesity or overweight a beneficial new treatment option to incorporate into a weight management program.  Both Semaglutide and Tirzapetide are intended for weight management in individuals with obesity or overweight conditions. They both work by targeting hormones involved in regulating appetite and metabolism to promote weight loss.  Personalizing your approachWhile seeing quick changes and results without much sacrifice is something most of us hope and strive for, it is important to recognize medication without calorie restriction and proper plan amounts to nothing. Personalizing your goals and expectations prior to initiating medication is crucial.  Steps to consider before treatment:  Insights into weight loss medication  We all know the frustration of sticking to a strict diet only not to see any results. It’s during these moments of disappointment you may wonder if there is an underlying medical issue affecting your progress and whether weight loss medications are for you however in doubt if they truly deliver results. Although obesity is prevailing, overweight drugs are rarely prescribed by doctors and are even less frequently used compared to medications for other medical conditions. why is that? There are conflicting opinions on whether obesity is a chronic condition or a disease as a whole. Although America is the first country to classify obesity as a disease, The World Health Organization (WHO) considers obesity only a serious problem. This prepares us to avoid expecting reimbursement for weight loss medications as it is not an available option in many countries. You would need to find out whether your government classifies obesity as a disease or not before your first purchase Are weight loss medications proven efficient?  Obesity is life-threatening however using slimming medicine without learning their safety through scientific studies is not recommended. Here’s what experts have to say about adding weight loss medication to your diet and the associated risks.  The New England Journal of Medicine reveals a recent study aimed to evaluate the efficacy of once weekly semaglutide (2.4 mg) alongside lifestyle intervention in facilitating weight loss among adults with obesity. The trial involved one thousand six hundred and one participants without diabetes, randomized to receive either semaglutide or a placebo over 68 weeks. Results demonstrated a substantial reduction in body weight among those receiving semaglutide compared to the placebo group. Participants on semaglutide exhibited a mean reduction of -14.9% in body weight, contrasting with -2.4% in the placebo group. This difference was statistically significant, indicating the effectiveness of semaglutide in promoting weight loss. The study also noted improvements in cardiometabolic risk factors and physical functioning among participants receiving semaglutide. The final analysis clinically concluded once weekly semaglutide (2.4 mg) in conjunction with lifestyle intervention demonstrated sustained and clinically relevant weight loss among adults who were overweight or obese.  The potential side effects of (Semaglutide and Tirzepatide) Both Semaglutide (Wegovy) and Tirzepatide (Zepbound), medications used for weight management, can have potential side effects. Common side effects of Semaglutide include nausea, diarrhea, vomiting, abdominal pain, and fatigue, while Tirzepatide may cause similar side effects along with injection site reactions, decreased appetite, and increased heart rate. Additionally, both medications may lead to hypoglycemia (low blood sugar), especially in individuals with diabetes, and rare cases of pancreatitis (inflammation of the pancreas) have been reported. It’s essential for individuals considering these medications to discuss potential side effects with their healthcare provider. Interested in learning more about the which medication might help you lose weight? Send us a message right away to get a free consultation from a weight loss expert or if you’re ready to start you journey check out our plans.