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Can Weight Loss Drugs Really Help with Addiction?

Can Weight Loss Drugs Really Help with Addiction?

Introduction Who would’ve thought that the same drugs helping people shed pounds might also kick some bad habits out the window? Yep, we’re talking about weight loss meds like Semaglutide and Tirzepatide potentially playing a role in addiction treatment. Sounds wild, right? But there’s some serious science behind this, and researchers are excited about where it might lead. It’s not every day that a medication designed for one thing ends up having the potential to help with something entirely different, but that’s exactly what’s happening here. The Surprising Link Between Weight Loss and Addiction So, what’s the connection? It all starts with a hormone called GLP-1 (glucagon-like peptide-1). Normally, when you eat, your pancreas pumps out GLP-1, which tells your brain, “Hey, you’re full. Put down the spoon!” This signaling is a critical part of keeping our appetite in check. But in people with conditions like obesity or diabetes, this signaling can get a little out of sync, leading to overeating. Your body basically forgets to tell you when you’ve had enough. That’s where weight loss drugs like Semaglutide come in. These drugs mimic GLP-1 to help get those hunger signals back on track. They act like GLP-1’s stunt double, making sure the message gets through loud and clear: Stop eating, you’re good! But here’s where things get interesting—GLP-1 doesn’t just mess with your appetite. It turns out, it also has a hand in how your brain’s reward system works. This is the same system that lights up when you do something that feels good, like eating your favorite food, winning a game, or, unfortunately, using addictive substances like nicotine, alcohol, or drugs. Researchers started to wonder—if GLP-1 can help curb food cravings, could it also help with other cravings? And that’s when things started to get interesting. How Do These Medications Mess with Your Brain? Let’s break it down a bit. The brain’s reward system is all about dopamine, the chemical that makes you feel good. Imagine dopamine as your brain’s way of giving you a high five whenever you do something that’s good for survival, like eating a meal or spending time with loved ones. It’s like a little internal cheerleader, encouraging you to keep doing things that are good for you. Normally, dopamine is great—it makes sure you keep doing things that are important for survival, like eating or socializing. But here’s the catch: addictive substances can hijack this system, making you crave more and more to get that same dopamine hit. It’s like your brain gets stuck in a loop, constantly seeking out the next hit, whether that’s from food, cigarettes, alcohol, or drugs. That’s basically how addiction takes hold. Now, GLP-1 agonists (fancy term for drugs like Semaglutide that mimic GLP-1) might help by reducing how much dopamine your brain pumps out in response to those addictive substances. In simple terms, these drugs could make your brain less excited about nicotine, alcohol, or even opioids, potentially helping to break the cycle of addiction. Imagine if your brain just stopped caring so much about that next cigarette or drink—it could be a game-changer. What’s the Evidence? So, is this all just a theory, or is there some proof? Researchers are on it! In one of the biggest studies so far, scientists tested another GLP-1 drug called exenatide on people with alcohol use disorder. The cool part? When these folks took exenatide, their brains didn’t light up as much when they saw booze, which suggests they weren’t craving it as much. But here’s the twist—this effect was strongest in people who were also dealing with obesity. That’s got researchers scratching their heads. Why would weight influence how well these drugs curb addiction? No one’s totally sure yet, but it could mean that GLP-1 drugs work better for some people than others. Or maybe there’s something special about how obesity and addiction interact. Either way, it’s got scientists eager to dig deeper. And that’s not all—there are studies underway looking at how these drugs might help with other addictions, like smoking and even opioid use. The possibilities are pretty exciting, but there’s still a lot we don’t know. The Safety Question Of course, nothing’s ever that simple, especially when it comes to meds. While GLP-1 drugs are generally safe for people using them to manage weight or diabetes, there are some concerns about using them to treat addiction. For starters, people who are malnourished or have certain health issues might not react well to these drugs. Imagine someone who’s struggling with a drug addiction—they might already be in poor health, and adding a new medication into the mix could have some unexpected effects. Plus, if GLP-1 drugs reduce dopamine too much, there’s a chance they could mess with your mood or motivation. Imagine feeling so “meh” that you lose interest in stuff you used to love—nobody wants that! It’s all about balance, and right now, we don’t know enough about how these drugs might affect people with different health backgrounds or levels of addiction. And let’s not forget about the side effects. Nausea and vomiting are common with these meds, which isn’t exactly fun. If you’re trying to get clean from an addiction, the last thing you need is to feel sick all the time, right? It could be enough to make someone quit the medication altogether, which would be a setback in their recovery journey. A Long Road Ahead So, what’s next? There’s still a lot to figure out. For one, the FDA hasn’t approved GLP-1 drugs for treating addiction yet. And while some researchers are running trials to see how well these drugs work for things like alcohol and opioid addiction, big pharma companies like Novo Nordisk and Eli Lilly are sticking to weight loss and diabetes for now. It’s a bit of a waiting game to see if these drugs really have what it takes to help people struggling with addiction. Even if these drugs do turn out to be a game-changer for addiction,

Can’t get insurance to approve weight loss drugs?

Can’t get insurance to approve weight loss drugs?

If you’ve watched TV or spent any time online lately, you’ve likely seen ads for weight loss drugs. They often highlight the dual benefits of not only shedding pounds but also managing diabetes. The results are undeniable, but there’s one major catch: these drugs come with a steep price tag. And if you’ve tried to get your insurance to cover them, you may have run into some frustrating roadblocks. Up to now, insurers have been reluctant to prescribe them! And in today’s blog, we will discuss the best ways to get your health plan to pay for your prescription and even methods you could use to lower the fees of your medications.  Back in the years, weight loss drugs have sometimes been considered a “lifestyle” or “cosmetic” issue. However, the World Health Organization (WHO) recognizes obesity as a chronic disease. This classification highlights that obesity is a long-term, relapsing condition that requires ongoing management, rather than just being a result of lifestyle choices or temporary weight gain.  Weight Loss Medication  Before we get to the ways to get your health plan to pay for your prescription, we need to understand what weight loss medication we are referring to and who are they geared towards. The category of medication we are talking about are GLP and GLP-1 agonists medication. You may have heard of Semaglutide and Tirzepatide, these are weight loss medications that work by mimicking the effects of a naturally occurring gut hormone.  In short, these are FDA-approved medications that contribute to weight loss up to 15 to 20 percent loss of body weight and both Semaglutide and Tirzepatide are both geared toward people with type 2 diabetes.  You can find more details about Semaglutide and Tirzepatide if you are interested in our website: https://naturopathicweightloss.com/blog/  What you should know It’s true that many employers and insurance plans don’t cover medications specifically for weight loss. You might wonder, though, if having a prescription from a doctor is enough for an insurer to cover the cost? Well, not necessarily, it is not often the only green light. If your doctor prescribes one of these drugs, there’s usually a process to follow. Often, your doctor will need to get prior authorization from the insurance company to cover the medication. This might involve filling out a form or writing a letter. The insurance plan typically wants to proof that you really need the drug. For example, if you have type 2 diabetes and need GLP-1 medication, you might need to show that you have diabetes and that you’ve tried other diabetes medications without success. They might also check if you meet specific criteria, like having a BMI of 30 or higher, or 27 or higher with a related health condition like high blood pressure. Additionally, they sometimes want to see that you’ve tried other weight loss methods, such as a structured program. Now, if your health plan covers GLP or GLP-1 medication, does that mean you’re off the hook for any out-of-pocket costs? It depends on your health plan. Anyone who has had different health plans knows that out-of-pocket costs can vary widely for the same treatment, depending on your employer or insurance provider. Sometimes, you might just have a flat co-pay like you do for many medications, but since these drugs are expensive, employers are cautious about the costs—both for individual patients and the number of people who might need them. Other options? So, if you’ve found out that your employer and insurance don’t cover your medication, does that mean you’re out of luck and won’t get the treatment you need?  Not at all!  There are plenty of rebates and discounts offered by manufacturers that can significantly lower the cost of these drugs—sometimes by over 50%. Other alternatives are prescription rate. “If you have diabetes and you can prove it, you can easily register for a prescription rate and receive discounts There are also other methods knowns as co-pay and co-insurance.  You may not be aware but your insurance plan might offer different ways to share the cost. Instead of having you pay the full price out-of-pocket, your plan could require a co-pay, which is a fixed amount you pay each time you fill the prescription. For example, you might pay a consistent $20 per refill, regardless of the medication’s actual cost.  Alternatively, your plan might involve co-insurance, where you pay a percentage of the medication’s price, such as 20%. This means if semaglutide costs $200, you would pay only $40.  It is understandable that all the methods mentioned can become overwhelming as it may involves contacting your insurance, your doctor and filling documents back and forth.  There are people who prefer turning to “Buy Now, Pay Later” (BNPL) options to help spread out these costs, making it easier to manage. With BNPL, you can break down the price of your medication into smaller, more affordable payments over time. For example, instead of paying $400 upfront for a month’s supply of semaglutide, you might pay $100 every two weeks for two months. This way, you get the medication you need right away, without straining your budget. Many companies offer these kinds of services, and they often don’t charge interest if you make your payments on time. Conclusion  Now the good news: these medications are already approved for treating diabetes and reducing cardiovascular risk, and there are more studies coming out soon that could lead to approvals for other conditions common in people who are obese, like chronic knee pain, osteoarthritis, and sleep apnea. If these new uses get approved, they could end up being covered by insurances.  Finger crossed but it seems that over the next few years, we’re likely to see more of these medications being approved and becoming more accessible through healthcare, even if congress doesn’t act right away. So, it’s a good bet that coverage will expand, and more people will be able to access these treatments.

How to Address Common Side Effects of Glp-01s with Naturopathic Supplements?

How to Address Common Side Effects of Glp-01s with Naturopathic Supplements?

Table of Contents Table Of Content Side Effects and Supplements Nausea Diarrhea Multiple Strains of Probiotics Pain in the Abdomen Overall Assistance with Digestion Conclusion Injectable anti-diabetic medications known as glucagon-like peptide-1 (GLP-1) receptor agonists help patients with type 2 diabetes (T2D) achieve better glycemic control and many other atherosclerosis-related metrics. Nonetheless, there might be potential negative consequences from using this relatively new class of medications. Since GLP-1 receptor agonists have been linked to pancreatitis, pancreatic cancer, and thyroid cancer in animal studies and drug database analysis, concerns have been raised about these medications’ impact on pancreatic and thyroid tissue. Nevertheless, a number of meta-analyses were unable to establish a causal relationship between GLP-1 receptor agonists and the emergence of these negative effects. Side Effects and Supplements: During GLP-1 receptor agonist clinical trials , the most commonly reported side effects were digestive issues. Probiotic pills with beneficial bacteria may help decrease symptoms of gastrointestinal side effects including nausea and diarrhea by restoring the balance of gut flora. A. Nausea: B. Diarrhea: It’s also important to know that probiotics can improve digestion and have a favorable effect on the balance of good bacteria in the stomach. i. Multiple Strains of Probiotics: Follow are the instructions on the packaging. ii. Pain in the Abdomen: iii. Overall Assistance with Digestion: Conclusion: Therefore, like it is often recommended with any new supplement, it is always wise to consult a doctor, especially if the patient is diabetic or has other chronic diseases that require they take other medications. It will be possible for them to ensure you that no harm comes with the vitamins or any other medication that you are currently taking.

The Powerful Science Behind Weight Loss Medication

The Powerful Science Behind Weight Loss Medication

Fighting against obesity is a challenging issue. This blog post aims to help you obtain a better understanding of the effects of weight loss medication on obesity and overweight Discover your hormonesGlucagon-like peptide-1 (GLP-1) and gastric inhibitory polypeptide (GIP) are two of the main incretin peptide hormones that are responsible for glucose homeostasis and enhance glucose-stimulated insulin secretion after nutrient ingest.  It is the successful application of incretin peptide hormones that have the potential to reduce weight and is considered an obesity treatment. GLP-1GLP-1 hormone is secreted predominantly in response to food intake to stimulate multiple glucose-lowering actions. Such as the secretion of glucose-insulin, delay in gastric emptying, and inhibition of glucagon secretion GIPOn the other hand, GIP is a peptide that is secreted in response to nutrient ingestion. GIP stimulates insulin secretion but does not change glucagon release during hyperglycemia (high levels of glucose in the blood), whereas it increases glucagon release without affecting insulin secretion during hypoglycemia (low levels of glucose in the blood). Peptide hormones using medicationNow, that you know which hormones are responsible for weight loss, the science behind weight loss medication becomes clearer. Recent evidence has shown that the combination of both GIP and GLP-1 through multiple metabolic mechanisms synergistically affect each other. In other words, they have a greater impact on the effectiveness of weight loss and glycemia. Additionally, the infusion of GLP-1 and GIP results in reduced food intake and appetite, thus lowering weight loss. The only FDA-approved medicine as a dual agonist of GIP and GLP-1, used for weight loss and T2D is known as Tirzepatide. Tirzepatide a promising anti-obesity therapeutic drug Analyses revealed that weight loss is particularly impacted by the dosage and duration of the Tirzepatide drug. Are you curious about what happens to your energy intake during treatment? Mechanistic studies have shown that tirzepatide 15 mg once a week reduces energy intake (–348.4 kcal) at full lunch in people with type 2 diabetes through reduction of the overall appetite, which explains the weight reduction. Semaglutide vs. Tirzepatide: Discover the Scientific DifferencesBoth semaglutide and tirzepatide have a strong effect on reducing glucose and body weight. Clinical studies have difficulties comparing both medications as more studies to confirm the findings are required. Nevertheless, here’s what the analysis revealed. In summary, understanding the role of GLP-1 and GIP in weight management opens new avenues for effective obesity treatment. Medications like Tirzepatide represent a significant advancement in obesity therapeutics, providing a scientifically-backed solution for those struggling with weight loss and associated metabolic conditions. As research continues, these medications offer a beacon of hope for improved health outcomes and better quality of life. Interested in learning more about the which medication might help you lose weight?Send us a message right away to get a free consultation from a weight loss expert or if you’re ready to start you journey check out our plans.

Semaglutide or Tirzepatide? Is Weight Loss Medication Right for You?

Semaglutide or Tirzepatide? Is Weight Loss Medication Right for You?

In a world where obesity is increasingly impairing health and many daily activities, a lot of people are turning to medical diagnoses seeking solutions to halt overweight consequences. The introduction of clinical weight loss drugs has seen new indications and concerns. In 2021, (FDA) Food & Drug Administration approved the very first under-the-skin injection, Wegovy (semaglutide), for chronic weight management in patients with a BMI of 27 kg/m2 or greater and to those linked to at least one “weight-related” health condition like high blood pressure diabetes or cholesterol while in 2022,  Zepbound (tirzepatide) injection was also approved by the FDA for the same conditions. Understanding weight loss medication  John Sharretts, M.D., deputy director of the Division of Diabetes, Lipid Disorders, and Obesity in the FDA’s Center for Drug Evaluation and Research says the approvals of the drug offer adults with obesity or overweight a beneficial new treatment option to incorporate into a weight management program.  Both Semaglutide and Tirzapetide are intended for weight management in individuals with obesity or overweight conditions. They both work by targeting hormones involved in regulating appetite and metabolism to promote weight loss.  Personalizing your approachWhile seeing quick changes and results without much sacrifice is something most of us hope and strive for, it is important to recognize medication without calorie restriction and proper plan amounts to nothing. Personalizing your goals and expectations prior to initiating medication is crucial.  Steps to consider before treatment:  Insights into weight loss medication  We all know the frustration of sticking to a strict diet only not to see any results. It’s during these moments of disappointment you may wonder if there is an underlying medical issue affecting your progress and whether weight loss medications are for you however in doubt if they truly deliver results. Although obesity is prevailing, overweight drugs are rarely prescribed by doctors and are even less frequently used compared to medications for other medical conditions. why is that? There are conflicting opinions on whether obesity is a chronic condition or a disease as a whole. Although America is the first country to classify obesity as a disease, The World Health Organization (WHO) considers obesity only a serious problem. This prepares us to avoid expecting reimbursement for weight loss medications as it is not an available option in many countries. You would need to find out whether your government classifies obesity as a disease or not before your first purchase Are weight loss medications proven efficient?  Obesity is life-threatening however using slimming medicine without learning their safety through scientific studies is not recommended. Here’s what experts have to say about adding weight loss medication to your diet and the associated risks.  The New England Journal of Medicine reveals a recent study aimed to evaluate the efficacy of once weekly semaglutide (2.4 mg) alongside lifestyle intervention in facilitating weight loss among adults with obesity. The trial involved one thousand six hundred and one participants without diabetes, randomized to receive either semaglutide or a placebo over 68 weeks. Results demonstrated a substantial reduction in body weight among those receiving semaglutide compared to the placebo group. Participants on semaglutide exhibited a mean reduction of -14.9% in body weight, contrasting with -2.4% in the placebo group. This difference was statistically significant, indicating the effectiveness of semaglutide in promoting weight loss. The study also noted improvements in cardiometabolic risk factors and physical functioning among participants receiving semaglutide. The final analysis clinically concluded once weekly semaglutide (2.4 mg) in conjunction with lifestyle intervention demonstrated sustained and clinically relevant weight loss among adults who were overweight or obese.  The potential side effects of (Semaglutide and Tirzepatide) Both Semaglutide (Wegovy) and Tirzepatide (Zepbound), medications used for weight management, can have potential side effects. Common side effects of Semaglutide include nausea, diarrhea, vomiting, abdominal pain, and fatigue, while Tirzepatide may cause similar side effects along with injection site reactions, decreased appetite, and increased heart rate. Additionally, both medications may lead to hypoglycemia (low blood sugar), especially in individuals with diabetes, and rare cases of pancreatitis (inflammation of the pancreas) have been reported. It’s essential for individuals considering these medications to discuss potential side effects with their healthcare provider. Interested in learning more about the which medication might help you lose weight? Send us a message right away to get a free consultation from a weight loss expert or if you’re ready to start you journey check out our plans.